Main Stage
- Friday 27 August 2010
- DIZZEE RASCAL
- THE CRIBS
- THE MACCABEES
- MODEST MOUSE
- THE GASLIGHT ANTHEM
- MYSTERY JETS
- THE FUTUREHEADS
- THE WALKMEN
- Saturday 28 August 2010
- WEEZER
- CYPRESS HILL
- LIMP BIZKIT
- YOU ME AT SIX
- ALL TIME LOW
- THRICE
- THE KING BLUES
- MOTION CITY SOUNDTRACK
- Sunday 29 August 2010
- BIFFY CLYRO
- LOSTPROPHETS
- NOFX
- GOGOL BORDELLO
- BILLY TALENT
- A DAY TO REMEMBER
- YOUNG GUNS
NME/Radio 1 Stage
- Friday 27 August 2010
- ENTER SHIKARI
- CRYSTAL CASTLES
- SERJ TANKIAN
- FRANK TURNER
- KIDS IN GLASS HOUSES
- HADOUKEN!
- 3OH!3
- BAND OF SKULLS
- EVERYTHING EVERYTHING
- ROLO TOMASSI
Lock Up Stage Dance Stage Lock Up Stage
- Friday 27 August 2010
- THE GET UP KIDS
- CANCER BATS
- ZEBRAHEAD
- TRASH TALK
- THE RATS
- PAINT IT BLACK
- OFF WITH THEIR HEADS
- RANDOM HAND
- MORAL DILEMMA
Festival Republic Stage
- Friday 27 August 2010
- ATARI TEENAGE RIOT
- THE BLACK ANGELS
- VILLAGERS
- GIGGS
- DARWIN DEEZ
- CHAPEL CLUB
- I BLAME COCO
- FREELANCE WHALES
- CHIEF
- THE CROOKES
- YUCK
- KASIUSS
BBC Introducing
- Friday 27 August 2010
- THE LAW
- SHOCKPARADE
- MOTION PICTURE SOUNDTRACK
- LOVE ENDS DISASTER
- MIDI MIDIS
- MY FOREVER
- THE INVASION OF
- LADY FORTUNE
- ROTATING LESLIE
- PENGUIN
- SOUL CIRCUS
- CLUB SMITH
The Alternative Stage
- Thursday 26 August 2010
- REBEL BINGO
- GOLDIEROCKS
- KICK-ASS
- Friday 27 August 2010
- RUSSELL KANE
- KEVIN BRIDGES
- TOM STADE
- RUFUS HOUND
- JJ WHITEHEAD
- MATT REED
- ROBIN INCE
- MATT KIRSHEN
- CHRISTIAN REILLY
- MC DAVE TWENTYMAN
- Instigate Debate
- TRASH HUMPERS
- SMASH & GRAB